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A Serine-Threonine Kinase (StkP) Regulates Expression of the Pneumococcal Pilus and Modulates Bacterial Adherence to Human Epithelial and Endothelial Cells In Vitro

The pneumococcal serine threonine protein kinase (StkP) acts as a global regulator in the pneumococcus. Bacterial mutants deficient in StkP are less virulent in animal models of infection. The gene for this regulator is located adjacent to the gene for its cognate phosphatase in the pneumococcal gen...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Herbert, Jenny A., Mitchell, Andrea M., Mitchell, Timothy J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474723/
https://ncbi.nlm.nih.gov/pubmed/26090876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127212
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