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Tetraploid Embryonic Stem Cells Maintain Pluripotency and Differentiation Potency into Three Germ Layers

Polyploid amphibians and fishes occur naturally in nature, while polyploid mammals do not. For example, tetraploid mouse embryos normally develop into blastocysts, but exhibit abnormalities and die soon after implantation. Thus, polyploidization is thought to be harmful during early mammalian develo...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Imai, Hiroyuki, Kano, Kiyoshi, Fujii, Wataru, Takasawa, Ken, Wakitani, Shoichi, Hiyama, Masato, Nishino, Koichiro, Kusakabe, Ken Takeshi, Kiso, Yasuo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474668/
https://ncbi.nlm.nih.gov/pubmed/26091100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130585
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