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The first murine zygotic transcription is promiscuous and uncoupled from splicing and 3′ processing

Initiation of zygotic transcription in mammals is poorly understood. In mice, zygotic transcription is first detected shortly after pronucleus formation in 1-cell embryos, but the identity of the transcribed loci and mechanisms regulating their expression are not known. Using total RNA-Seq, we have...

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Bibliografski detalji
Izdano u:EMBO J
Glavni autori: Abe, Ken-ichiro, Yamamoto, Ryoma, Franke, Vedran, Cao, Minjun, Suzuki, Yutaka, Suzuki, Masataka G, Vlahovicek, Kristian, Svoboda, Petr, Schultz, Richard M, Aoki, Fugaku
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474528/
https://ncbi.nlm.nih.gov/pubmed/25896510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490648
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