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Profile of evolocumab and its potential in the treatment of hyperlipidemia

Despite the proven efficacy of statins, they often fail to achieve low-density lipoprotein (LDL) cholesterol goals, especially in high-risk patients. Moreover, a large number of subjects cannot tolerate statins or full doses of these drugs, in particular patients with familial hypercholesterolemia....

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Cicero, Arrigo FG, Colletti, Alessandro, Borghi, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474387/
https://ncbi.nlm.nih.gov/pubmed/26109850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S67498
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