Tet1 Regulates Adult Hippocampal Neurogenesis and Cognition

DNA hydroxylation catalyzed by Tet dioxygenases occurs abundantly in embryonic stem cells and neurons in mammals. However, its biological function in vivo is largely unknown. Here we demonstrate that Tet1 plays an important role in regulating neural progenitor cell proliferation in adult mouse brain...

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Publicado en:Cell Stem Cell
Autores principales: Zhang, Run-Rui, Cui, Qing-Yan, Murai, Kiyohito, Lim, Yen Ching, Smith, Zachary D., Jin, Shengnan, Ye, Peng, Rosa, Luis, Lee, Yew Kok, Wu, Hai-Ping, Liu, Wei, Xu, Zhi-Mei, Yang, Lu, Ding, Yu-Qiang, Tang, Fuchou, Meissner, Alexander, Ding, Chunming, Shi, Yanhong, Xu, Guo-Liang
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474382/
https://ncbi.nlm.nih.gov/pubmed/23770080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.05.006
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