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Patient-derived hepatitis C virus inhibits CD4(+) but not CD8(+) T lymphocyte proliferation in primary T cells
BACKGROUND: Hepatitis C virus (HCV) can replicate in cells of the immune system and productively propagate in primary T lymphocytes in vitro. We aimed to determine whether exposure to authentic, patient-derived HCV can modify the proliferation capacity, susceptibility to apoptosis and phenotype of T...
Guardat en:
| Publicat a: | Virol J |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4474354/ https://ncbi.nlm.nih.gov/pubmed/26084511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0322-4 |
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