ATP Depletion Via Mitochondrial F(1)F(0) Complex by Lethal Factor is an Early Event in B. Anthracis-Induced Sudden Cell Death

Bacillus anthracis’ primary virulence factor is a tripartite anthrax toxin consisting of edema factor (EF), lethal factor (LF) and protective antigen (PA). In complex with PA, EF and LF are internalized via receptor-mediated endocytosis. EF is a calmodulin-dependent adenylate cyclase that induces ti...

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Detalhes bibliográficos
Publicado no:J Cell Death
Main Authors: Woodberry, Mitchell W., Aguilera-Aguirre, Leopoldo, Bacsi, Attila, Chopra, Ashok K., Kurosky, Alexander, Peterson, Johnny W., Boldogh, Istvan
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2009
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474334/
https://ncbi.nlm.nih.gov/pubmed/26124678
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