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Crystal Structures of Yeast-Produced Enterovirus 71 and Enterovirus 71/Coxsackievirus A16 Chimeric Virus-Like Particles Provide the Structural Basis for Novel Vaccine Design against Hand-Foot-and-Mouth Disease

Human enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) are the two major causative agents for hand-foot-and-mouth disease (HFMD). Previously, we demonstrated that a virus-like particle (VLP) for EV71 produced from Saccharomyces cerevisiae is a potential vaccine candidate against EV71 infection,...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Lyu, Ke, He, Ya-Ling, Li, Hao-Yang, Chen, Rong
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474312/
https://ncbi.nlm.nih.gov/pubmed/25833050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00422-15
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