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Regulation of Hepatitis C Virus Genome Replication by Xrn1 and MicroRNA-122 Binding to Individual Sites in the 5′ Untranslated Region

miR-122 is a liver-specific microRNA (miRNA) that binds to two sites (S1 and S2) on the 5′ untranslated region (UTR) of the hepatitis C virus (HCV) genome and promotes the viral life cycle. It positively affects viral RNA stability, translation, and replication, but the mechanism is not well underst...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Thibault, Patricia A., Huys, Adam, Amador-Cañizares, Yalena, Gailius, Julie E., Pinel, Dayna E., Wilson, Joyce A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474307/
https://ncbi.nlm.nih.gov/pubmed/25855736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03631-14
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