Ox40L–Ox40 pathway plays distinct roles in regulating Th2 responses but does not determine outcome of cutaneous leishmaniasis caused by Leishmania mexicana and Leishmania major

Ox40 ligand (Ox40L)–Ox40 pathway has been shown to enhance Th2 responses and play a role in pathogenesis of cutaneous leishmaniasis (CL) caused by Leishmania major. Using Ox40l(−/−) BALB/c mice we analyzed the role of this pathway in determining the outcome to CL caused by L. mexicana and compared t...

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Bibliographic Details
Published in:Exp Parasitol
Main Authors: Tuladhar, Rashmi, Oghumu, Steve, Dong, Ran, Peterson, Allison, Sharpe, Arlene H., Satoskar, Abhay R.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474147/
https://ncbi.nlm.nih.gov/pubmed/25447125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2014.11.002
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