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Paclitaxel-Releasing Thin Biodegradable Film for Prevention of Bleb Avascularity Without Compromising Filtration in Rabbits

PURPOSE: A honeycomb-patterned film (HPF) prevents bleb scarring and mitomycin C (MMC)-related bleb avascularity in a rabbit model of filtration surgery. In this study, we examined whether a HPF-releasing paclitaxel (PTX) can prevent bleb avascularity without compromising filtration. METHODS: Filtra...

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Detalhes bibliográficos
Publicado no:Transl Vis Sci Technol
Main Authors: Okuda, Tetsuhiko, Higashide, Tomomi, Sakurai, Mayumi, Fukuhira, Yukako, Kaneko, Hiroaki, Shimomura, Masatsugu, Sugiyama, Kazuhisa
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473721/
https://ncbi.nlm.nih.gov/pubmed/26101723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.4.3.10
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