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Novel small-molecule SIRT1 inhibitors induce cell death in adult T-cell leukaemia cells
Adult T-cell leukaemia/lymphoma (ATL) is an aggressive T-cell malignancy that develops after long-term infection with human T-cell leukaemia virus (HTLV)-1. The identification of new molecular targets for ATL prevention and treatment is desired. SIRT1, a nicotinamide adenine dinucleotide(+) -depende...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4473680/ https://ncbi.nlm.nih.gov/pubmed/26091232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11345 |
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