Recombination Analysis of Herpes Simplex Virus 1 Reveals a Bias toward GC Content and the Inverted Repeat Regions

Herpes simplex virus 1 (HSV-1) causes recurrent mucocutaneous ulcers and is the leading cause of infectious blindness and sporadic encephalitis in the United States. HSV-1 has been shown to be highly recombinogenic; however, to date, there has been no genome-wide analysis of recombination. To addres...

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Bibliographic Details
Published in:J Virol
Main Authors: Lee, Kyubin, Kolb, Aaron W., Sverchkov, Yuriy, Cuellar, Jacqueline A., Craven, Mark, Brandt, Curtis R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473588/
https://ncbi.nlm.nih.gov/pubmed/25926637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00880-15
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