Hepatitis B Virus-Infected HepG2(hNTCP) Cells Serve as a Novel Immunological Tool To Analyze the Antiviral Efficacy of CD8(+) T Cells In Vitro

CD8(+) T cells are the main effector lymphocytes in the control of hepatitis B virus (HBV) infection. However, limitations of model systems, such as low infection rates, restrict mechanistic studies of HBV-specific CD8(+) T cells. Here, we established a novel immunological cell culture model based o...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hoh, Alexander, Heeg, Maximilian, Ni, Yi, Schuch, Anita, Binder, Benedikt, Hennecke, Nadine, Blum, Hubert E., Nassal, Michael, Protzer, Ulrike, Hofmann, Maike, Urban, Stephan, Thimme, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473563/
https://ncbi.nlm.nih.gov/pubmed/25972537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00605-15
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