Inefficient Codon Usage Impairs mRNA Accumulation: the Case of the v-FLIP Gene of Kaposi's Sarcoma-Associated Herpesvirus

Latent Kaposi's sarcoma-associated herpesvirus (KSHV) genomes encode a homolog of cellular FLICE-inhibitory proteins (termed v-FLIP) that activates NF-κB and can trigger important proinflammatory and antiapoptotic changes in latently infected cells. The protein is present at very low levels in...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Bellare, Priya, Dufresne, Andrew, Ganem, Don
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473549/
https://ncbi.nlm.nih.gov/pubmed/25926644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03390-14
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