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Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against glioblastoma

INTRODUCTION: The median survival of patients with glioblastoma multiforme (astrocytoma grade 4) remains less than 18 months despite radical surgery, radiotherapy and systemic chemotherapy. Surgical implantation of chemotherapy eluting wafers into the resection cavity has been shown to improve lengt...

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Detalhes bibliográficos
Publicado no:Ann R Coll Surg Engl
Main Authors: Smith, SJ, Rahman, CV, Clarke, PA, Ritchie, AA, Gould, TW, Ward, JH, Shakesheff, KM, Grundy, RG, Rahman, R
Formato: Artigo
Idioma:Inglês
Publicado em: Royal College of Surgeons 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473433/
https://ncbi.nlm.nih.gov/pubmed/25245726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1308/003588414X13946184903568
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