Eosinophil-specific deletion of IκBα in mice reveals a critical role of NF-κB–induced Bcl-x(L) for inhibition of apoptosis

Eosinophils are associated with type 2 immune responses to allergens and helminths. They release various proinflammatory mediators and toxic proteins on activation and are therefore considered proinflammatory effector cells. Eosinophilia is promoted by the cytokines interleukin (IL)-3, IL-5, and gra...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Schwartz, Christian, Willebrand, Ralf, Huber, Silke, Rupec, Rudolf A., Wu, Davina, Locksley, Richard, Voehringer, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473117/
https://ncbi.nlm.nih.gov/pubmed/25862560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-607788
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