Maleic Acid – but Not Structurally Related Methylmalonic Acid – Interrupts Energy Metabolism by Impaired Calcium Homeostasis

Maleic acid (MA) has been shown to induce Fanconi syndrome via disturbance of renal energy homeostasis, though the underlying pathomechanism is still under debate. Our study aimed to examine the pathomechanism underlying maleic acid-induced nephrotoxicity. Methylmalonic acid (MMA) is structurally si...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tuncel, Ali Tunç, Ruppert, Thorsten, Wang, Bei-Tzu, Okun, Jürgen Günther, Kölker, Stefan, Morath, Marina Alexandra, Sauer, Sven Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473014/
https://ncbi.nlm.nih.gov/pubmed/26086473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128770
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