Mitochondrial Ultrastructural Alterations and Declined M(2) Receptor Density Were Involved in Cardiac Dysfunction in Rats after Long Term Treatment with Autoantibodies against M(2) Muscarinic Receptor

BACKGROUND: Previous studies showed that autoantibodies (M(2)-AA) against the second extracellular loop of M(2) muscarinic receptor (M(2)AChR-el2) from dilated cardiomyopathy (DCM) serum could induce DCM-like morphological changes in mice hearts. However, the effects of M(2)-AA on the cardiac functi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhang, Suli, He, Zhongmei, Wang, Jin, Wang, Li, Wu, Ye, Wang, Jie, Lv, Tingting, Liu, Huirong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472961/
https://ncbi.nlm.nih.gov/pubmed/26086781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129563
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