Homozygous Wildtype of XPD K751Q Polymorphism Is Associated with Increased Risk of Nasopharyngeal Carcinoma in Malaysian Population

The xeroderma pigmentosum group D (XPD) gene encodes a DNA helicase, an important component in transcription factor IIH (TFIIH) complex. XPD helicase plays a pivotal role in unwinding DNA at the damaged region during nucleotide excision repair (NER) mechanism. Dysfunctional XPD helicase protein from...

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Pubblicato in:PLoS One
Autori principali: Lye, Munn-Sann, Visuvanathan, Shaneeta, Chong, Pei-Pei, Yap, Yoke-Yeow, Lim, Chin-Chye, Ban, Eng-Zhuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472930/
https://ncbi.nlm.nih.gov/pubmed/26086338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130530
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