Specific sequences from the carboxyl terminus of human p53 gene product form anti-parallel tetramers in solution.
Human p53 is a tumor-suppressor gene product associated with control of the cell cycle and with growth suppression, and it is known to form homotetramers in solution. To investigate the relationship of structure to tetramerization, nine peptides corresponding to carboxyl-terminal sequences in human...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1994
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44729/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8090755/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.19.8974 |
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