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Analysis of Low Frequency Protein Truncating Stop-Codon Variants and Fasting Concentration of Growth Hormone

BACKGROUND: The genetic background of Growth Hormone (GH) secretion is not well understood. Mutations giving rise to a stop codon have a high likelihood of affecting protein function. OBJECTIVES: To analyze likely functional stop codon mutations that are associated with fasting plasma concentration...

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Pubblicato in:PLoS One
Autori principali: Hallengren, Erik, Almgren, Peter, Engström, Gunnar, Persson, Margaretha, Melander, Olle
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472854/
https://ncbi.nlm.nih.gov/pubmed/26086970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128348
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