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Small Conductance Calcium-Activated Potassium Current is Important in Transmural Repolarization of Failing Human Ventricles

BACKGROUND: The transmural distribution of apamin-sensitive small conductance Ca(2+)-activated K(+) (SK) current (I(KAS)) in failing human ventricles remains unclear. METHODS AND RESULTS: We optically mapped left ventricular wedge preparations from 12 failing native hearts and 2 rejected cardiac all...

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Detalhes bibliográficos
Publicado no:Circ Arrhythm Electrophysiol
Main Authors: Yu, Chih-Chieh, Corr, Christopher, Shen, Changyu, Shelton, Richard, Yadava, Mrinal, Rhea, Isaac, Straka, Susan, Fishbein, Michael C., Chen, Zhenhui, Lin, Shien-Fong, Lopshire, John C., Chen, Peng-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472528/
https://ncbi.nlm.nih.gov/pubmed/25908692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.114.002296
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