Mitochondrial Dysfunction Induced by N-Butyl-1-(4-Dimethylamino)Phenyl-1,2,3,4-Tetrahydro-β-Carboline-3-Carboxamide Is Required for Cell Death of Trypanosoma cruzi

BACKGROUND: Chagas’ disease is caused by the protozoan Trypanosoma cruzi and affects thousands of people worldwide. The available treatments are unsatisfactory, and new drugs must be developed. Our group recently reported the trypanocidal activity of the synthetic compound N-butyl-1-(4-dimethylamino...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Volpato, Hélito, Desoti, Vânia Cristina, Valdez, Rodrigo Hinojosa, Ueda-Nakamura, Tânia, Silva, Sueli de Oliveira, Sarragiotto, Maria Helena, Nakamura, Celso Vataru
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472351/
https://ncbi.nlm.nih.gov/pubmed/26086449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130652
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