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Antigen-Conjugated Human IgE Induces Antigen-Specific T Cell Tolerance in a Humanized Mouse Model

Dendritic cells (DCs) play an important role in immune homeostasis through their ability to present Ags at steady state and mediate T cell tolerance. This characteristic renders DCs an attractive therapeutic target for the induction of tolerance against auto-antigens or allergens. Accordingly, Ag-co...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Baravalle, Günther, Greer, Alexandra M., LaFlam, Taylor N., Shin, Jeoung-Sook
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472313/
https://ncbi.nlm.nih.gov/pubmed/24610015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301751
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