Oleanolic acid induces mitochondrial-dependent apoptosis and G0/G1 phase arrest in gallbladder cancer cells

Oleanolic acid (OA), a naturally occurring triterpenoid, exhibits potential antitumor activity in many tumor cell lines. Gallbladder carcinoma is the most common malignancy of the biliary tract, and is a highly aggressive tumor with an extremely poor prognosis. Unfortunately, the effects of OA on ga...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Li, Huai-Feng, Wang, Xu-An, Xiang, Shan-Shan, Hu, Yun-Ping, Jiang, Lin, Shu, Yi-Jun, Li, Mao-Lan, Wu, Xiang-Song, Zhang, Fei, Ye, Yuan-Yuan, Weng, Hao, Bao, Run-Fa, Cao, Yang, Lu, Wei, Dong, Qian, Liu, Ying-Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2015
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472077/
https://ncbi.nlm.nih.gov/pubmed/26109845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S84448
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