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Clinical utility of naloxegol in the treatment of opioid-induced constipation

Opioids are a class of medications frequently used for the treatment of acute and chronic pain, exerting their desired effects at central opioid receptors. Agonism at peripherally located opioid receptors, however, leads to opioid-induced constipation (OIC), one of the most frequent and debilitating...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Pain Res
Hauptverfasser: Bruner, Heather C, Atayee, Rabia S, Edmonds, Kyle P, Buckholz, Gary T
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472065/
https://ncbi.nlm.nih.gov/pubmed/26109876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S61326
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