Dominant Driving Forces in Human Telomere Quadruplex Binding-Induced Structural Alterations

Recently various pathways of human telomere (ht) DNA folding into G-quadruplexes and of ligand binding to these structures have been proposed. However, the key issue as to the nature of forces driving the folding and recognition processes remains unanswered. In this study, structural changes of 22-m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Bončina, Matjaž, Hamon, Florian, Islam, Barira, Teulade-Fichou, Marie-Paule, Vesnaver, Gorazd, Haider, Shozeb, Lah, Jurij
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2015
Schlagworte:
Proteins and Nucleic Acids
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472043/
https://ncbi.nlm.nih.gov/pubmed/26083930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.05.001
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