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CpG oligodeoxyribonucleotide 7909 enhances radiosensitivity via downregulating Oct-4 expression in radioresistant lung cancer cells

Radiotherapy is a powerful cure for local advanced non-small cell lung cancer. However, radioresistance and tumor relapse still occur in a high proportion of patients. Octamer-4 (Oct-4), a transcription factor of the POU family, plays a key role in maintaining chemoradioresistant properties and regu...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Xing, Na, Qiao, Tiankui, Zhuang, Xibing, Yuan, Sujuan, Zhang, Qi, Xu, Guoxiong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472028/
https://ncbi.nlm.nih.gov/pubmed/26109868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S84467
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