The Presence of Genetic Mutations at Key Loci Predicts Progression to Esophageal Adenocarcinoma in Barrett's Esophagus

OBJECTIVES: Risk stratification in Barrett's esophagus (BE) is challenging. We evaluated the ability of a panel of genetic markers to predict progression to high-grade dysplasia (HGD) or esophageal adenocarcinoma (EAC). METHODS: In this case–control study, we assessed a measure of genetic insta...

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Bibliographic Details
Published in:Am J Gastroenterol
Main Authors: Eluri, Swathi, Brugge, William R, Daglilar, Ebubekir S, Jackson, Sara A, Styn, Mindi A, Callenberg, Keith M, Welch, Derek C, Barr, Todd M, Duits, Lucas C, Bergman, Jacques J, Shaheen, Nicholas J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
Subjects:
Esophagus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471888/
https://ncbi.nlm.nih.gov/pubmed/26010308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2015.152
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