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Interleukin-33 in tissue homeostasis, injury and inflammation

Interleukin-33 (IL-33) is a nuclear-associated cytokine of the IL-1 family originally described as a potent inducer of allergic type 2 immunity. IL-33 signals via the receptor ST2, which is highly expressed on group 2 innate lymphoid cells (ILC2s) and T helper 2 (Th2) cells, thus underpinning its as...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Molofsky, Ari B., Savage, Adam, Locksley, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471869/
https://ncbi.nlm.nih.gov/pubmed/26084021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.06.006
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