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Significant cytostatic effect of everolimus on a gefitinib-resistant anaplastic thyroid cancer cell line harboring PI3KCA gene mutation

We previously demonstrated the efficacy of gefitinib, a tyrosine kinase inhibitor of the epidermal growth factor receptor (EGFR), on an anaplastic thyroid cancer (ATC) cell line. We also observed that gefitinib was not effective in regulating cell growth in a different ATC cell line that exhibited a...

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Detalhes bibliográficos
Publicado no:Mol Clin Oncol
Main Authors: ONODA, NAOYOSHI, NAKAMURA, MASANORI, AOMATSU, NAOKI, NODA, SATORU, KASHIWAGI, SHINICHIRO, KURATA, KENTO, UCHINO, SHINYA, HIRAKAWA, KOSEI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471583/
https://ncbi.nlm.nih.gov/pubmed/26137260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2015.496
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