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Prevalence of Germline Mutations in Genes Engaged in DNA Damage Repair by Homologous Recombination in Patients with Triple-Negative and Hereditary Non-Triple-Negative Breast Cancers

PURPOSE: This study sought to assess the prevalence of common germline mutations in several genes engaged in the repair of DNA double-strand break by homologous recombination in patients with triple-negative breast cancers and hereditary non-triple-negative breast cancers. Tumors deficient in this t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Domagala, Pawel, Jakubowska, Anna, Jaworska-Bieniek, Katarzyna, Kaczmarek, Katarzyna, Durda, Katarzyna, Kurlapska, Agnieszka, Cybulski, Cezary, Lubinski, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471155/
https://ncbi.nlm.nih.gov/pubmed/26083025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130393
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