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Merkel Cell Carcinoma with a Suppressor of Fused (SUFU) Mutation: Case Report and Potential Therapeutic Implications

INTRODUCTION: Merkel cell carcinoma is a neuroendocrine malignancy. Suppressor of fused (SUFU) is a tumor suppressor oncogene that participates in the Hedgehog (Hh) signaling pathway. The aim of the study was to describe a patient whose Merkel cell carcinoma demonstrated a SUFU genomic alteration. C...

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Publicat a:Dermatol Ther (Heidelb)
Autors principals: Cohen, Philip R., Kurzrock, Razelle
Format: Artigo
Idioma:Inglês
Publicat: Springer Healthcare 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470960/
https://ncbi.nlm.nih.gov/pubmed/25876211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13555-015-0074-5
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