Grade-dependent metabolic reprogramming in kidney cancer revealed by combined proteomics and metabolomics analysis

Kidney cancer (or renal cell carcinoma [RCC]) is known as “the internist’s tumor” because it has protean systemic manifestations suggesting it utilizes complex, non-physiologic metabolic pathways. Given the increasing incidence of this cancer and its lack of effective therapeutic targets, we underto...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Wettersten, Hiromi I., Hakimi, A. Ari, Morin, Dexter, Bianchi, Cristina, Johnstone, Megan E., Donohoe, Dallas R., Trott, Josephine F., Aboud, Omran Abu, Stirdivant, Steven, Neri, Bruce, Wolfert, Robert, Stewart, Benjamin, Perego, Roberto, Hsieh, James J., Weiss, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470795/
https://ncbi.nlm.nih.gov/pubmed/25952651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1703
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