Utilizing Microchip Capillary Electrophoresis Electrospray Ionization for Hydrogen Exchange Mass Spectrometry

Hydrogen exchange (HX) mass spectrometry (MS) of complex mixtures requires a fast, reproducible, and high peak capacity separation prior to MS detection. The current paradigm relies on liquid chromatography (LC) with fast gradients performed at low temperatures to minimize back exchange. Unfortunate...

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Publicado en:Anal Chem
Main Authors: Black, William A., Stocks, Bradley B., Mellors, J. Scott, Engen, John R., Ramsey, J. Michael
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470751/
https://ncbi.nlm.nih.gov/pubmed/25992468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b01179
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