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Pareto Optimization Identifies Diverse Set of Phosphorylation Signatures Predicting Response to Treatment with Dasatinib

Multivariate biomarkers that can predict the effectiveness of targeted therapy in individual patients are highly desired. Previous biomarker discovery studies have largely focused on the identification of single biomarker signatures, aimed at maximizing prediction accuracy. Here, we present a differ...

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Publicat a:PLoS One
Autors principals: Klammer, Martin, Dybowski, J. Nikolaj, Hoffmann, Daniel, Schaab, Christoph
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470654/
https://ncbi.nlm.nih.gov/pubmed/26083411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128542
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