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Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome

The short rib polydactyly syndromes (SRPS) are a heterogeneous group of autosomal recessive, perinatal-lethal skeletal disorders characterized primarily by short, horizontal ribs, short limbs, and poly-dactyly. Mutations in several genes affecting intraflagellar transport (IFT) cause SRPS but they d...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Taylor, S. Paige, Dantas, Tiago J., Duran, Ivan, Wu, Sulin, Lachman, Ralph S., Nelson, Stanley F., Cohn, Daniel H., Vallee, Richard B., Krakow, Deborah
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470332/
https://ncbi.nlm.nih.gov/pubmed/26077881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8092
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