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Can Novel Treatment of Age-Related Macular Degeneration Be Developed by Better Understanding of Sorsby’s Fundus Dystrophy

Sorsby’s Fundus Dystrophy (SFD) is a rare autosomal dominant maculopathy that shares many clinical features with Age-Related Macular Degeneration (AMD). It is caused by a mutation in a single gene, TIMP-3, which accumulates in Bruch’s membrane (BM). BM thickening and TIMP-3 accumulation can also be...

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Détails bibliographiques
Publié dans:J Clin Med
Auteurs principaux: Gourier, Hanae C. Y., Chong, N. Victor
Format: Artigo
Langue:Inglês
Publié: MDPI 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470204/
https://ncbi.nlm.nih.gov/pubmed/26239453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm4050874
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