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Targeted Therapy of FLT3 in Treatment of AML—Current Status and Future Directions
Internal tandem duplications (ITDs) of the gene encoding the Fms-Like Tyrosine kinase-3 (FLT3) receptor are present in approximately 25% of patients with acute myeloid leukemia (AML). The mutation is associated with poor prognosis, and the aberrant protein product has been hypothesized as an attract...
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| Pubblicato in: | J Clin Med |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4470194/ https://ncbi.nlm.nih.gov/pubmed/26237612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm3041466 |
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