A non-tight junction function of claudin-7—Interaction with integrin signaling in suppressing lung cancer cell proliferation and detachment

BACKGROUND: Claudins are a family of tight junction (TJ) membrane proteins involved in a broad spectrum of human diseases including cancer. Claudin-7 is a unique TJ membrane protein in that it has a strong basolateral membrane distribution in epithelial cells and in tissues. Therefore, this study ai...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Lu, Zhe, Kim, Do Hyung, Fan, Junming, Lu, Qun, Verbanac, Kathryn, Ding, Lei, Renegar, Randall, Chen, Yan-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470020/
https://ncbi.nlm.nih.gov/pubmed/26081244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0387-0
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