Caspase-1 inhibitor ameliorates experimental autoimmune myasthenia gravis by innate dendric cell IL-1-IL-17 pathway

BACKGROUND: IL-1β has been shown to play a pivotal role in autoimmunity. Cysteinyl aspartate-specific proteinase-1 (caspase-1) inhibitor may be an important drug target for autoimmune diseases. However, the effects of caspase-1 inhibitor on myasthenia gravis (MG) remain undefined. METHODS: To invest...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Wang, Cong-Cong, Li, Heng, Zhang, Min, Li, Xiao-Li, Yue, Long-Tao, Zhang, Peng, Zhao, Yue, Wang, Shan, Duan, Ruo-Nan, Li, Yan-Bin, Duan, Rui-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470006/
https://ncbi.nlm.nih.gov/pubmed/26071315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0334-4
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