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The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.

The multidrug-resistance associated protein MRP is a 180- to 195-kDa membrane protein associated with resistance of human tumor cells to cytotoxic drugs. We have investigated how MRP confers drug resistance in SW-1573 human lung carcinoma cells by generating a subline stably transfected with an expr...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Zaman, G J, Flens, M J, van Leusden, M R, de Haas, M, Mülder, H S, Lankelma, J, Pinedo, H M, Scheper, R J, Baas, F, Broxterman, H J
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1994
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44698/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7916458/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.19.8822
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