Exchange of Cone for Rod Phosphodiesterase 6 Catalytic Subunits in Rod Photoreceptors Mimics in Part Features of Light Adaptation

Despite the expression of homologous phototransduction components, the molecular basis for differences in light-evoked responses between rod and cone photoreceptors remains unclear. We examined the role of cGMP phosphodiesterase (PDE6) in this difference by expressing cone PDE6 (PDE6C) in rd1/rd1 ro...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Majumder, Anurima, Pahlberg, Johan, Muradov, Hakim, Boyd, Kimberly K., Sampath, Alapakkam P., Artemyev, Nikolai O.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469743/
https://ncbi.nlm.nih.gov/pubmed/26085644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3563-14.2015
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