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Pronounced reversible hyperammonemic encephalopathy associated with combined valproate–topiramate therapy in a 7-year-old girl

Valproate is one of the most frequently used anticonvulsive drugs in children and adults. Valproate is a generally well tolerated medication. However, encephalopathy with or without hyperammonemia is one of its rare adverse events. We present a 7-year-old girl who suffered from epilepsy with general...

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Veröffentlicht in:Springerplus
Hauptverfasser: Weise, Sebastian, Syrbe, Steffen, Preuss, Matthias, Bertsche, Astrid, Merkenschlager, Andreas, Bernhard, Matthias K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469596/
https://ncbi.nlm.nih.gov/pubmed/26090323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-015-1057-9
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