Integration of computational modeling with membrane transport studies reveals new insights into amino acid exchange transport mechanisms

Uptake of system L amino acid substrates into isolated placental plasma membrane vesicles in the absence of opposing side amino acid (zero-trans uptake) is incompatible with the concept of obligatory exchange, where influx of amino acid is coupled to efflux. We therefore hypothesized that system L a...

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Vydáno v:FASEB J
Hlavní autoři: Widdows, Kate L., Panitchob, Nuttanont, Crocker, Ian P., Please, Colin P., Hanson, Mark A., Sibley, Colin P., Johnstone, Edward D., Sengers, Bram G., Lewis, Rohan M., Glazier, Jocelyn D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2015
Témata:
Research Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469330/
https://ncbi.nlm.nih.gov/pubmed/25761365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-267773
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