Retargeting pre-existing human antibodies to a bacterial pathogen with an alpha-Gal conjugated aptamer

The ever-increasing threat of multi-drug resistant bacterial infections has spurred renewed interest in alternative approaches to classical antibiotic therapy. In contrast to other mammals, humans do not express the galactose-α-1,3-galactosyl-β-1,4-N-acetyl-glucosamine (α-Gal) epitope. As a result o...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Mol Med (Berl)
Hlavní autoři: Kristian, Sascha A., Hwang, John H., Hall, Bradley, Leire, Emma, Iacomini, John, Old, Robert, Galili, Uri, Roberts, Charles, Mullis, Kary B., Westby, Mike, Nizet, Victor
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469262/
https://ncbi.nlm.nih.gov/pubmed/25940316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-015-1280-4
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky