Aspirin Prevents Colorectal Cancer by Normalizing EGFR Expression

BACKGROUND: Aspirin intake reduces the risk of colorectal cancer (CRC), but the molecular underpinnings remain elusive. Epidermal growth factor receptor (EGFR), which is overexpressed in about 80% of CRC cases, is implicated in the etiology of CRC. Here, we investigated whether aspirin can prevent C...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Main Authors: Li, Haitao, Zhu, Feng, Boardman, Lisa A., Wang, Lei, Oi, Naomi, Liu, Kangdong, Li, Xiang, Fu, Yang, Limburg, Paul J., Bode, Ann M., Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2015
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469241/
https://ncbi.nlm.nih.gov/pubmed/26097892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.03.019
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