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Interleukin-12 suppresses filaria-induced pulmonary eosinophilia, deposition of major basic protein and airway hyperresponsiveness

Tropical Pulmonary Eosinophilia (TPE) is a severe form of allergic asthma caused by the host inflammatory response to filarial helminths in the lung microvasculature, and is characterized by pulmonary eosinophilia, increased filarial-specific IgG and IgE antibodies, and airway hyperresponsiveness. T...

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Bibliographic Details
Published in:Parasite Immunol
Main Authors: MEHLOTRA, RAJEEV K., HALL, LAURIE R., HIGGINS, ALAN W., DRESHAJ, ISMAIL A., HAXHIU, MUSA A., KAZURA, JAMES W., PEARLMAN, ERIC
Format: Artigo
Language:Inglês
Published: 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469192/
https://ncbi.nlm.nih.gov/pubmed/9797506
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