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Regulation of DCIS to invasive breast cancer progression by Singleminded-2s (SIM2s)
Singleminded-2s (SIM2s) is a member of the bHLH/PAS family of transcription factors and a key regulator of mammary epithelial cell differentiation. SIM2s is highly expressed in mammary epithelial cells and down regulated in human breast cancer. Loss of Sim2s causes aberrant mouse mammary ductal deve...
Gespeichert in:
| Veröffentlicht in: | Oncogene |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4469191/ https://ncbi.nlm.nih.gov/pubmed/22777354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.286 |
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